The Arrests of woot and reid

On April 9 2012, a statement of facts was filed at the Eastern District of Virginia Court after a plea bargain was reached regarding a charge of conspiracy to import an analogue controlled substance. Justin Steven Scroggins, also known as woot from the online drug discussion forum euphoricknowledge.com, pled guilty to the charge. The statement of facts was in large part similar to the indictment posted previously, but also contains additional detail of his arrest.

On April 10, 2012, Scroggins was arrested in Jacksonville, Florida. He was given his legal rights and elected to waive them in writing. Scroggins admitted that he had set up his own website, www.euphoricknowledge.com, in August 2011 to compete with another drug website on which he had previously sold synthetic drugs. Scroggins not only marketed drugs on his website, but also sold advertising space on the site for $200 to $400 per month. In November 2011, Scroggins began using the name Micro Nutrient Supply (MNS) to market synthetic cannabinoids from the AM and JWH series of compounds. He then expanded his market to include 5-MeO-MiPT, 5-MeO-DALT, A-PVP, MXE, 4-EMC, 4-MEC, and etizolam. Scroggins admitted to importing his drugs into the United States from three different laboratories in China. Scroggins stated that he would label his blends and other products “not for human consumption” but he admitted “I know what it is … people buy this stuff to get high.”

Scroggins admitted to special agents that he had placed an order for A-PVP, pentylone, pentedrone, 4-MEC and other drugs from reidtang, one of the contacts at a Chinese lab, through CD#1 in Virginia on April 5, 2012. He stated that he wanted to place the order through CD#1 because the drug bans were much less stringent in Virginia than in Florida. Scroggins and CD#1 had both ordered and received analogue drugs from reidtang prior to the April order.

In a consent search of the defendant’s residence, agents recovered three plastic bags containing 4-MEC and UR-144, which had been placed in the toilet for disposal but did not go down the drain. The plastic bag containing the drugs was submitted to the Department of Homeland Security US Customs and Border Protection Laboratory. The lab determined that there was 24.24 grams of 4-MEC and UR-144 in a small bag, 120.36 grams of 4-MEC in a large bag, and plant material which contained 45.64 grams of 4-MEC.

Further, agents recovered mixing jars, rubber gloves, a grinder, USPS packing/mailing boxes and envelopes, packaging materials, tobacco flavorings, a desktop computer, a USB drive and a Sprint cell phone. In addition, $1636 in US currency was recovered.

On September 5 2012, the contact at the Chinese lab named in the statement of facts “reidtang” was allegedly arrested as well. This appears to be a coordinated effort between US and Chinese authorities.

our company no long existed since reid has been arrested by the china GOV.
he was arrested at 5th,SEP,and still haven’t been able to release so far,all the stocks of our chems and money have been confiscated by the police.
we’re realy sorry for this happened,we never scammed any of the customers,but,we have no money to compensate for your loss……….
the situation here seems quite not optimistic here,the GOV is seaching for RCs source……
best regards,

The Fall of Euphoric Knowledge

On April 9 2012, an affidavit was filed at the Eastern District of Virginia Court describing an offense of conspiracy to import an analogue controlled substance. The affidavit was submitted in support for an arrest warrant for Justin Steven Scroggins, also known as woot who ran the online drug discussion forum Euphoric Knowledge. Selected excepts follow, edited for clarity.

Since early February 2012, I have been investigating a loosely affiliated organization of individuals throughout the United States that are involved in the large scale importation of synthetic drugs from laboratories in China into the United States and the subsequent nationwide distribution of those drugs. Through the course of the investigation, I have identified Justin Steven Scroggins, aka “Woot”, aka “Dirk McDiggler” as an individual involved in these activities. Scroggins was initially identified by a cooperating defendant (CD#1) in this investigation.

Through the review of recorded telephone conversations, internet chats, and video teleconferencing activities, I have become acutely aware of Scroggins and his drug trafficking activities. On an almost daily basis since March 16, 2012, Scroggins has been observed discussing his use, importation and distribution of various controlled substances including, but not limited to: cocaine, marijuana, and various synthetic drugs covered under the Federal Analogue Act. Scroggins has been observed discussing methods by which he receives payment for his drug trafficking activities, disguises his income, and launders the proceeds. Scroggins has also discussed, on several occasions, planning to launder money for a profit for vendors on his website euphoricknowledge.com.

I reviewed a video recording taken April 5, 2012 in which Scroggins, CD#1, and a third individual “reidtang” conducted a recorded three-way videoconference. The purpose of this teleconference was for Scroggins to discuss importing several synthetic drugs from reidtang’s laboratory in China into the United States via CD#1. Scroggins expressed his intent to sent approximately $5000 via express mail to CD#1 so that CD#1 could purchase the drugs from reidtang on Scroggins’ behalf. Scroggins stated that he wished for CD#1 to purchase the following on his behalf:

1 kilogram of 4-MEC
500 grams of A-PVP
250 grams of pentylone
250 grams of pentedrone
25 grams of D2PM
25 grams of 4-MBC
25 grams of A-PBP

(These substances are analogues of scheduled controlled substances banned by federal law. As they are chemically similar in structure and have the same basic physiological effects as the controlled substances, these substances are banned under 21 U.S.C. Section 813, as Schedule I controlled substances.)

On the video recording Scroggins stated that he intentionally wished to conduct the transaction in this fashion saying “I don’t wanna get any of that shit here because I don’t wanna have any issues goin’ to fuckin’ jail over it.” Scroggins also added that “I’m pretty sure they went through one of my packages, they didn’t open the packages, but they opened the documentation for it, they were reading the slips.” Scroggins also commented on other difficulties with increasingly stringent synthetic drug bans in Florida.

In addition to the recorded video teleconferencing, Scroggins, CD#1, and reidtang were conducting a simultaneous text chat. During this text chat, Scroggins told reidtang “so total of about $6000, I will send money to CD#1, he can bankwire no issues :) ” to which reidtang responded “k good”. Reidtang then informed Scroggins he has methoxetamine for sale. Scroggins responded “nice as long as it is good quality, rcsupplier sent me a batch of fucking white crap. I can maybe snort 100mg, small effect, haha and it makes my throat feel scratchy. Feels like I’ve been snorting a razor.” Scroggins subsequently sent CD#1 an internet chat message with the tracking number for the currency being mailed to CD#1.

On the morning of April 7, 2012, I along with another member of the investigative team intercepted the package of US currency being shipped to CD#1 from Scroggins. The package was a letter size US Postal Service Express Mail envelope. The package was seized and opened with the consent of CD#1. Inside this envelope as a sealed US Postal Service Priority Mail envelope which contained a sealed white plastic envelope, which in turn contained a sealed manila envelope, which contained a sealed brown paper envelope, which finally contained $4600 US currency. The tracking number on this package was the same tracking number provided the previous day by Scroggins.

Based on the previous, I submit that there is probable cause to believe that Scroggins aka w00t and others, some of whom are not yet known or fully identified, have committed the offense described above.

A short message was posted on the website euphoricknowledge.com confirming these events.

Dear users of Euphoric Knowledge,

It is in this time of great duress we must inform you about what has been going on, and what the current site admins have been trying to cover up.

Woot has indeed been arrested and is in custody. We have little faith that he will not roll on us. Here is proof of his arrest

(link to affidavit)

As you can see, woot has been in custody since April 10. The DEA has sealed the case as an “ongoing investigation” which means EK is likely compromised beyond salvation. Resu and MrMike are not to be trusted, as they have been trying to cover up these allegations, even going so far as to say he would post from woot’s account to reassure everyone. Their nonchalant attitude here seems to indicate his own LEO involvement, or at least a blatant disregard for the member’s safety by covering up this event. They specifically requested the staff not tell anyone what had happened.

This is coming from the entire moderation staff. We have convened long and hard about this. Following this post we will likely be banned.

We extend a hand of friendship to you members to reconvene with us at

rcbay.org

It is a nonprofit site. Vendors do not pay to be sponsored. The domain is hosted in russia, out of the USA’s jurisdiction.

In this time of great strife, we must remember to be strong. We are still a community.
We advise you to take measures to protect yourselves. Delete incrimination posts, etc

Godspeed,
The EK Moderation team

The site mentioned as a euphoricknowledge.com replacement, rcbay.org, does not currently appear to be operational.

4-Hydroxy Tryptamines

The indole ring of tryptamine provides a number of possible locations for functional groups to be substituted. Addition of a hydroxy group at the 4-position produces a large number of active psychedelic compounds including some true classics.

4-hydroxylation of alpha substituted tryptamines such as AMT has been conducted but further exploration has been limited due to potential toxic effects.

The 4-hydroxy analogue of α-MT has been looked at in human subjects. It is reported to be markedly visual in its effects, with some subjects reporting dizziness and a depressed feeling. There were, however, several toxic signs at doses of 15 to 20 milligrams orally, including abdominal pain, tachycardia, increased blood pressure and, with several people, headache and diarrhea.

-Alexander Shulgin

4-hydroxylation of the n-alkylated tryptamines is more fruitful. For instance, 4-hydroxylation of DMT (dimethyltryptamine) produces the classic psilocin (4-HO-DMT, 4-hydroxy-dimethyltryptamine). These 4-hydroxy n-alkyl tryptamines are similar in general psychedelic character, moderately potent (active at 10-25 mg) and of medium duration (2-6 hours).

Other functional groups can be substituted at the 4-position which are converted to 4-HO tryptamines in the human body. Psilocybin (4-PO-DMT, 4-phosphoryloxy-dimethyltryptamine) contained in psychedelic mushrooms is water soluble and too polar to cross the blood-brain barrier. After consumption phosphatase enzymes rapidly break apart the phosphoryloxy group producing the active psilocin (4-HO-DMT, 4-hydroxy-dimethyltryptamine).

The phosphoryl group in psilocybin that is cleaved off by enzymes is known as an ester, and other esters can be substituted that react in similar ways once consumed by man.

O-acetylpsilocin (4-AcO-DMT, 4-acetoxy-dimethyltryptamine) can be thought of as psilocybin with an acetoxy group instead of a phosphoryloxy group. Like psilocybin, it is rapidly converted to 4-HO-DMT in the body. This produces a compound with a similar subjective experience to that of psilocybin.

4-HO tryptamines can therefore have a 4-AcO pair with very similar effects. The 4-AcO partner tends to be slightly less potent, have a longer duration, and be subjectively “smoother” than the 4-HO counterpart. It is a matter of debate whether this is simply the result of varying rates of administration due to metabolic conversion, or if 4-AcO tryptamines are active in their own right.

Shulgin, A. #48 AMT. Tryptamines I Have Known and Loved. Transform Press, 1997.

Vito Cozzi, Nicholas. MAPS: Re: Psilocybin and the blood brain barrier. MAPS Forum, April 29 2003.

Leminger’s Scalines

Otakar Leminger was a little-known Czechoslovakian chemist who worked for years in industry and lived on the banks of the Elbe River in Ústí north of Prague. When he retired in the early 1970s he published a paper entitled “A Contribution to the Chemistry of Alkoxylated Phenethylamines” in which he describes the synthesis of several novel phenethylamines which he tested on himself to determine activity.

(1) allylescaline, 3,5-dimethoxy-4-allyloxy-phenethylamine (2) proscaline, 3,5-dimethoxy-4-n-propoxy-phenethylamine (3) escaline, 3,5-dimethoxy-4-ethoxy-phenethylamine (4) MAPEA, 3-methoxy-4-allyloxy-phenethylamine (5) MEPEA, 3-methoxy-4-ethoxy-phenethylamine

We can classify the compounds he discussed into two groups depending on the number of ring substitutions. Allylescaline, proscaline, and escaline have three while MAPEA and MEPEA have two. Generally phenethylamines with two ring substitutions are not active, but Leminger had found some exceptions. This knowledge might have been lost to time if not for the fact that Stanislov Wistupkin brought the paper to the attention of Alexander Shulgin.

[MAPEA and MEPEA are some] of the few phenethylamines with only two substituents that show even a hint of central activity. And there is an interesting story attached. I got a call out of absolutely nowhere, from a Stanislov Wistupkin, that he had discovered a number of new psychedelic drugs which he would like to share with me. They were simple phenethylamines, one with an ethoxy group at the 4-position, and one with an allyloxy group there. Both, he said, were mood elevators active between 100 and 300 milligrams. One of them was a material called MEPEA, and the other one was 3-methoxy-4-allyloxyphenethylamine, or MAPEA. When I did meet him in person, he gave me a most remarkable publication which had been authored some ten years earlier, by a person named Leminger, now dead. It was all in Czech, but quite unmistakably, right there on the third page, were the structures of MEPEA and MAPEA, and the statement that they were active at between 100 and 300 milligrams.

- Alexander Shulgin

MAPEA and MEPEA are only mildly active and interesting mostly in the sense that they appear to be the exception to the rule that phenethylamines with two ring substitutions are inactive. Leminger also created several mescaline variants with three ring substitutions by modifying the methoxy group at the 4 position and replacing it with an allyloxy, propoxy, or ethoxy group. The resulting compounds allylescaline, proscaline, and escaline were then tested on himself and found to be much more potent and intriguing.

Physiological effects of the compounds were examined only approximately on my body. The sulphate salts of MEPEA and MAPEA in doses 0.1-0.3 g were mild mood-elevators and were also cough calming agents. Allylescaline, proscaline, and escaline were much more active. Qualitatively there wasn’t a big difference among them and quantitatively their effect decreased: allylescaline was more potent than proscaline, and proscaline more potent than escaline. As an example the allylescaline experience is described:

“One hour after a 20 mg dose of allylescaline: perhaps slight vertigo, light drunkeness and pleasant excitation with locomotion need was observed. Eye perceptions were pricked up, colours seemed to be more warm and objects more plastic. Surroundings were much more interesting than usual. Colourful hallucinations were observed in the dark. Moreover, a calming effect to the breathing system and some kind of constriction of the digestive system was observed. Sleep at night was restless with megalomaniacal fantasies. Even 12 h after administration the effects were present. More serious studies of physiological activity are in contemplation.”

- Otakar Leminger

Leminger was the first to synthesize and consume allylescaline, the most potent of the mescaline derivatives explored. He was able to identify active phenethyamines with only two ring substitutions, a notoriously unproductive class of compounds. Did he conduct additional experimentation and screening beyond that detailed in this paper? No other publications by Leminger relating to psychedelic compounds are known.

Might there be other treasures that he had discovered, and never published? Was young Wistupkin a student of his? Are there unrecognized notes of Otakar Leminger sitting in some farm house attic in Northern Czechoslovakia? I extend my heartfelt salute to an almost unknown explorer in the psychedelic drug area.

- Alexander Shulgin

Otakar Leminger, A Contribution to the Chemistry of Alkoxylated Phenethylamines – Part 2. Chemicky Prumysl 22, 553 (1972).

Alexander Shulgin, #2 Allylescaline. Phenethylamines I Have Known and Loved, Transform Press (1991).

Alexander Shulgin, #123 MEPEA. Phenethylamines I Have Known and Loved, Transform Press (1991).

N-Alkylated Tryptamines

The amine group of tryptamine possesses a nitrogen with two hydrogens where functional groups can be substituted. Let’s start with the simple case where both of these substitutions are identical. The best known example is dimethyltryptamine, abbreviated as DMT (D for di meaning two, M for the methyl alkyl substitions, and T for the tryptamine backbone). There are other tryptamines like DMT with longer symmetrical alkyl chains which have similar effects and are named in a similar manner.


Some dialkylated tryptamines: dimethyltryptamine (DMT), diethyltryptamine (DET), dipropyltryptamine (DPT), dibutyltryptamine (DBT).

DMT is typically smoked as other consumption routes are ineffective due to MAO degradation, but the longer alkyl chains do not have this issue and are all orally active. There is no theoretical limit to the alkyl chain length, but potency decreases as chain length increases. DBT is the longest simple chain dialkylated tryptamine commonly bioassayed in man.

We can also consider asymmetrical cases where the two substitutions are different. The possible combinations quickly increase in number as the following table up to alkyl chains of three carbons in size illustrates. Asymmetric compounds are referred to by giving initials to both of their substitutions (shortest chain first) and ending with a T to signify the tryptamine backbone.

methyl ethyl propyl isopropyl
(none) NMT NET NPT NiPT
methyl DMT MET MPT MiPT
ethyl DET EPT EiPT
propyl DPT PiPT
isopropyl DiPT

Linked compounds have a full entry in TiHKAL.

These two rulesets for symmetric and asymmetric substitutions allow us to refer to a huge variety of n-alkylated tryptamines using abbreviations in a simple and consistent manner.

Shulgin, A. #2 DBT. Tryptamines I Have Known and Loved. Transform Press, 1997.

Alpha Substituted Tryptamines

The tryptamine backbone provides a building block for a large number of research chemicals. One such class is the alpha-substituted tryptamines. There are two carbons between the amine group (NH2) and the indole ring of tryptamine, referred to as alpha and beta.

Short alkyl chains have successfully been substituted at the alpha position nearest the amine group. These include compounds such as AMT and AET, which are releasing agents of serotonin, norepinephrine, and dopamine resulting in stimulating and euphoric effects. At higher doses their psychedelic character becomes more prominent. Potency decreases as alkyl chain length increases, and alpha-propyltryptamine has not been widely explored.

What about substitution on the beta carbon instead? It doesn’t seem hopeful. Substitution at the alpha carbon acts to protect the compound against enzymatic degradation but the beta position does not have this advantage. Little actual data regarding synthesis or effects are available however, and this remains an unexplored possibility.

Biosynthesis of 4-Substituted Tryptamine Derivatives

Biological organisms are wondrous little molecular factories, their enzyme catalyzed reactions often accomplishing in a single step what would confound a chemist in a well-stocked laboratory. Researchers have attempted to harness these biosynthetic pathways to create complex molecules not easily synthesized by conventional methods.

Psilocybin is produced via a biosynthetic grid where enzymes act on various closely related intermediate compounds in turn. The enzymes do not appear to be particularly picky about the compounds they modify. For instance, dimethyltryptamine (DMT) is hydroxylated to 4-HO-DMT naturally in psilocybin mushrooms. Other precursor compounds like tryptamine and methyltryptamine are also hydroxlyated to 4-hydroxy-tryptamine and 4-hydroxy-methyltryptamine respectively.

If an entirely new synthetic tryptamine of similar structure was introduced to these mushrooms, would the same enzymes act on it? This could produce a new and unique psychedelic compound where some of the heavy lifting of synthesis is accomplished by the biological expertise of the mushroom itself and not by conventional laboratory chemistry.

Jochen Gartz decided to attempt this by adding diethyltryptamine (DET, a close relative of DMT) to the fruiting body of psilocybe cubensis. He hoped that it would be hydroxylated to 4-HO-DET, or possibly phosphorylated even further to 4-PO-DET. He first colonized a mixture of cow dung and rice grain with psilocybe cubensis, and then injected it with a solution of DET. Within four weeks mushrooms were produced, and five total flushes of mushrooms were obtained.

First Second Third Fourth Fifth
4-HO-DET 2.5% 0.2% 3.1% 3.3% 2.1%
4-PO-DET - 0.8% 0.01% - 0.02%

all values % by weight of dry mushroom

The project was a success, with significant amounts of 4-HO-DET produced. No DET was found in the dried mushrooms. A mass balance was not conducted to determine the efficiency of the conversion and possible losses in the fruiting body itself. The demonstrated non-selectivity of the enzymes in psilocybe cubensis toward other tryptamine derivatives opened to the door to the possibility of producing truly exotic and difficult to synthesize compounds such as 4-HO-5-MeO-DMT.

Despite this little additional data is available on the tryptamine derivatives that are able to be substituted in the fruiting body and the repeatability of the experiment. Some have found little success, noting only a decrease in the size of the mushrooms produced. Other attempts have discovered perhaps a qualitative difference in potency and character of the psychedelic experience, but this has not been substantiated by quantitative measurement.


Biotransformation of tryptamine derivatives in mycelial cultures of Psilocybe
. Gartz, J. Journal of Basic Microbiology, Volume 29, Issue 6, Pages 347-352 (1989).

Why Does Cannabis Potentiate Psychedelics?

It’s an effect that many psychedelic users are familiar with – at the tail end of trip, with the experience waning, smoking cannabis will tend to increase the psychedelic effects and “bring the trip back”. Similar effects occur on the comedown of drugs like MDMA. Why does this happen?

It appears that this may be a result of the interrelationship between the brain’s natural cannabinoid receptors and the GABA system.

Nerve cells are designed to fire repetitively, and are subject to a barrage of stimuli. The brain prevents itself from spiraling out of control into hyperexcitable states by inhibition, a way of “turning down the volume” in the brain. The major workhorse for this is gamma animobutyric acid, or GABA. In a strange parallel, the brain synthesizes GABA in one step from glutamate, the brain’s major excitatory neurotransmitter.

We know that cannabis gets us “high”, that it produces a general excitatory effect across many areas of the brain. First this was thought to be a result of cannabinoid (specifically CB1) receptors being expressed on glutamate receptors. This was not the case. Instead, they appear to be almost exclusively expressed on GABAergic neurons where they have an inhibitory effect.

So it seems that cannabis inhibits the inhibitor, and ends up having a general excitatory effect. In the same manner that a benzodiazepine or alcohol may dull a trip via direct GABA agonism, cannabis may increase the effects of a waning psychedelic due to GABA inhibition.

Cannabinoids inhibit hippocampal GABAergic transmission and network oscillations. N. Hajos et. al. European Journal of Neuroscience, Vol. 12, pp. 3239-3249, 2000.

Grid Biosynthesis of Psilocybin

The biosynthesis of psilocybin in psychedelic mushrooms is a multi-step process, and the precise mechanism is debated by many authors. The essential amino acid l-tryptophan undergoes several modifying reactions (decarboxylation, N-methylation, 4-hydroxylation, and O-phosphorylation) but the specific order is unclear. A series of steps similar to the following is generally accepted.

Experiments with radiolabled precursors have shown that this is likely the primary path to psilocybin, however, labelled 4-hydroxytryptamine was also shown to be incorporated into the produced psilocybin indicating the possibility of an additional biosynthetic pathway. Other alkaloids present in psilocybin mushrooms such as baeocystin or norbaeocystin are not explained by this single pathway as well.

An elegant alternative has been proposed. What if instead of a single path and a set order of modifying reactions, there were multiple paths to psilocybin – with branching edges that led to baeocystin and norbaeocystin? The enzymes would compete and feed back among each other in a biosynthetic grid that preferred to produce psilocybin and psilocin but also produced small amounts of baeocystin and norbaeocystin as typically seen in nature.

There is no longer a preferred order to the modifying reactions, except for the obvious that 4-hydroxylation must precede O-phosphorylation. There are three paths to psilocin and psilocybin (the predominant alkaloids in psychedelic mushrooms), two paths to baeocystin (found in lesser concentrations than the two signature alkaloids), and one path to norbaeocystin (found in the lowest concentrations, if it is detectable at all). The number of paths does not indicate the absolute likelihood of producing a certain alkaloid, but it can be seen as a measure of resiliency. The precise weighting of each connection in the network is not clear at this point, or even if a steady state model would be an appropriate approximation.

Biosynthesis of Psilocybin. Part II: Introduction of Labelled Tryptamine Derivatives. S. Agurell and J. Lars G. Nilsson. Acta Chemica Scandinavica 22 (1968), 1210-1218.

Baeocystin and Norbaeocystin: New Analogs of Psilocybin from Psilocybe baeocystis. A.Y. Leung and A.G. Paul. Journal of Pharmaceutical Sciences, Vol. 57, No. 10, October 1968, 1667-1671.

Tryptamines as Ligands and Modulators of the Serotonin 5-HT2A Receptor and the
Isolation of Aeruginascin from the Hallucinogenic Mushroom Inocybe aeruginascens
. Niels Jensen, Dissertation zur Erlangung des Doktorgrades der Mathematisch-Naturwissenschaftlichen Fakultäten der Georg-August-Universität zu Göttingen, 2004.

Non-LSD Ergoloids

The research chemical market is based on the philosophy of tweaking existing recreational molecular backbones, yet compounds based on LSD appear to be few and far between. There is nothing at all preventing the existence of exotic research chemicals based on the ergoloid backbone, and in fact several are known that have significant recreational potential based on academic studies. The interesting fact is that none of them appear to have hit the market in significant volume. Perhaps this is simply the result of watched precursors and more elaborate synthesis routes than established products, but experimentation by the research chemical market seems rather lackluster based on the reputation of the parent drug and possible potential.

There are some who argue that experimentation of this nature has been ongoing, but has been executed through entirely different distribution channels – namely the LSD black market. Certain blotter prints have been distributed with something that could pass for LSD but seems different to experienced tastes. This particular variant has been described as a sort of neo-LSD that appears more euphoric, more visual, shorter acting, and less “spiritual” with the accompanying decrease in potential for anxiety.

One suspected blotter print is the 1906-2008 Hoffman Oms. This is not a esoteric print with limited circulation. It celebrates the life of Albert Hofmann, who lived from 1906 to 2008 and was the first to synthesize and consume LSD. It is part of a larger recurring blotter art series that is consistently widely distributed and well received, and as such appears to originate from the depths of the notoriously secretive LSD black market.

Sufficient suspicions were raised about the contents of this blotter to instigate a GC/MS test.

Initial evaluation seemed to bear out the hypothesis that these results reflected a novel and interesting compound closely related to LSD, perhaps lysergic acid 2-butyl amide (LSB) or lysergic acid 3-pentyl amide (LSP). These early interpretations of the GC/MS results were challenged however.

sec-LSB gives an almost indistinguishable MS to actual LSD, so I doubt it’s that. It’s not the N-(3-Pentyl) derivative [..] as well[.]

I personally have not a clue what this is — the fragment for d-Lysergic acid diethylamide, LAMPA or sec-LSB is always at 324, yet here we have 326 (the only one that comes to mind is deuterated-LSD which is usually 327). The huge peak at 72 is suspicious and the initial peaks at 44/58 as well (small substituted amines?).

296-208 is usual fragment for N-Et-LSD and a peak adjacent to 209 is present
310-209 characteristic of nor-LSD/nor-iso-LSD

So, you’re missing quite a bunch of the normal peaks but you have what might be degradation products or side impure product present, but it seems pretty inconclusive.

-nuke

Unfortunately it appears that no clear conclusions can be drawn. The blotter cannot be positively identified as LSD, but it also cannot be identified as a closely related compound or even as a completely different psychedelic compound. These blotters were clearly active in man, and displayed a psychedelic character very close to LSD. The major issue is lack of comprehensive test results, as GC/MS analysis is not easily available. Even if these tests are conducted, the data is not typically shared widely. It seems likely that these problems will become more manageable as technology progresses.

It is very likely that closely related compounds to LSD have been synthesized and tested in man. The precursors are available, the skills are out there, and the desire exists. Whether these exotic relatives of the world’s most famous psychedelic remain limited to a select few or have been surreptitiously released on a wider scale to a mostly unaware public remains to be seen.

Bluelight Forum > Focus Forums > Psychedelic Drugs > The Big & Dandy Non-LSD Ergoloids Blotter Thread.